BDBM50227827 (E)-5-(3-oxo-3-phenylprop-1-enyl)-6-phenylpyridazin-3(2H)-one::5-(3-Oxo-3-phenyl-propenyl)-6-phenyl-2H-pyridazin-3-one::5-(3-oxo-3-phenylprop-1-enyl)-6-phenylpyridazin-3(2H)-one::CHEMBL392224

SMILES: O=C(C=Cc1cc(=O)[nH]nc1-c1ccccc1)c1ccccc1

InChI Key: InChIKey=SXSWFYPYIIBACL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50227827 ((E)-5-(3-oxo-3-phenylprop-1-enyl)-6-phenylpyridazi...) Show SMILES O=C(C=Cc1cc(=O)[nH]nc1-c1ccccc1)c1ccccc1 |w:3.3| Show InChI InChI=1S/C19H14N2O2/c22-17(14-7-3-1-4-8-14)12-11-16-13-18(23)20-21-19(16)15-9-5-2-6-10-15/h1-13H,(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of thrombin-induced platelet aggregation				Bioorg Med Chem Lett 16: 1080-3 (2006) Article DOI: 10.1016/j.bmcl.2005.10.073 BindingDB Entry DOI: 10.7270/Q2F76C37
					More data for this Ligand-Target Pair