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SMILES: FC(F)(F)c1cc(NC(=O)NC2CCN(CCC3CCS(=O)(=O)C3)CC2)cc(c1)C(F)(F)F

InChI Key: InChIKey=SIOWVROFOZTBLX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227872   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50227872
PNG
(1-(3,5-bis-trifluoromethyl-phenyl)-3-{1-[2-(1,1-di...)
Show SMILES FC(F)(F)c1cc(NC(=O)NC2CCN(CCC3CCS(=O)(=O)C3)CC2)cc(c1)C(F)(F)F |w:17.16|
Show InChI InChI=1S/C20H25F6N3O3S/c21-19(22,23)14-9-15(20(24,25)26)11-17(10-14)28-18(30)27-16-2-6-29(7-3-16)5-1-13-4-8-33(31,32)12-13/h9-11,13,16H,1-8,12H2,(H2,27,28,30)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 1.10E+3n/an/an/an/an/an/an/an/a



UCB Inflammation Discovery

Curated by ChEMBL


Assay Description
Antagonist activity at human CXCR3 by [35S]GTPgammaS binding assay

Bioorg Med Chem Lett 18: 147-51 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.109
BindingDB Entry DOI: 10.7270/Q2MC8ZRG
More data for this
Ligand-Target Pair