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BDBM50227934 CHEMBL75371

SMILES: Cc1cc(C)c(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c(C)c1

InChI Key: InChIKey=PUESRTPEYCCVDE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227934   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)		BDBM50227934
PNG
(CHEMBL75371)
Show SMILES Cc1cc(C)c(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c(C)c1
Show InChI InChI=1S/C24H26N2O/c1-18-14-19(2)23(20(3)15-18)25-24(27)26(16-21-10-6-4-7-11-21)17-22-12-8-5-9-13-22/h4-15H,16-17H2,1-3H3,(H,25,27)
PDB

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UniProtKB/SwissProt

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PC sid
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PubMed
n/an/a 3.62E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals

J Med Chem 32: 2318-25 (1989)


BindingDB Entry DOI: 10.7270/Q2QZ2D5R
More data for this
Ligand-Target Pair