BDBM50228428 CHEMBL238706::diphenyl 1-amino-2-(4-guanidinophenyl)ethylphosphonate

SMILES: [#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key: InChIKey=KBAIUJQIGXFZDI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50228428 (CHEMBL238706 | diphenyl 1-amino-2-(4-guanidinophen...) Show SMILES [#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1 Show InChI InChI=1S/C21H23N4O3P/c22-20(15-16-11-13-17(14-12-16)25-21(23)24)29(26,27-18-7-3-1-4-8-18)28-19-9-5-2-6-10-19/h1-14,20H,15,22H2,(H4,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human uPA				J Med Chem 50: 6638-46 (2007) Article DOI: 10.1021/jm700962j BindingDB Entry DOI: 10.7270/Q2MW2J0J
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