BDBM50228429 CHEMBL442768

SMILES: CC1CC(=O)NN=C1c1ccc2OC(C)C(=O)N(C)c2c1

InChI Key: InChIKey=UNWSWLMWFUXBFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50228429 (CHEMBL442768) Show SMILES CC1CC(=O)NN=C1c1ccc2OC(C)C(=O)N(C)c2c1 |c:6| Show InChI InChI=1S/C15H17N3O3/c1-8-6-13(19)16-17-14(8)10-4-5-12-11(7-10)18(3)15(20)9(2)21-12/h4-5,7-9H,6H2,1-3H3,(H,16,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.				J Med Chem 33: 380-6 (1990) BindingDB Entry DOI: 10.7270/Q241708F
					More data for this Ligand-Target Pair