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SMILES: CC1CC(=O)NN=C1c1ccc2NC(=O)C(C)Oc2c1

InChI Key: InChIKey=QVIVLZURJARBGA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228451   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50228451
PNG
(CHEMBL124587)
Show SMILES CC1CC(=O)NN=C1c1ccc2NC(=O)C(C)Oc2c1 |c:6|
Show InChI InChI=1S/C14H15N3O3/c1-7-5-12(18)16-17-13(7)9-3-4-10-11(6-9)20-8(2)14(19)15-10/h3-4,6-8H,5H2,1-2H3,(H,15,19)(H,16,18)
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PC cid
PC sid
UniChem
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.

J Med Chem 33: 380-6 (1990)


BindingDB Entry DOI: 10.7270/Q241708F
More data for this
Ligand-Target Pair