BDBM50228463 CHEMBL123668

SMILES: CS(=O)(=O)N1CCOc2ccc(cc12)C1=NNC(=O)CC1

InChI Key: InChIKey=NRSUTOOICJSLBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50228463 (CHEMBL123668) Show SMILES CS(=O)(=O)N1CCOc2ccc(cc12)C1=NNC(=O)CC1 |t:16| Show InChI InChI=1S/C13H15N3O4S/c1-21(18,19)16-6-7-20-12-4-2-9(8-11(12)16)10-3-5-13(17)15-14-10/h2,4,8H,3,5-7H2,1H3,(H,15,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.				J Med Chem 33: 380-6 (1990) BindingDB Entry DOI: 10.7270/Q241708F
					More data for this Ligand-Target Pair