BDBM50228825 CHEMBL2112409

SMILES: COc1ccc(cc1O[C@@H]1CC2CC1C1CCCC21)C1CNC(=O)N1C

InChI Key: InChIKey=FHWOSRUUSHMKKA-IJNOCJQWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Rattus norvegicus)	BDBM50228825 (CHEMBL2112409) Show SMILES COc1ccc(cc1O[C@@H]1CC2CC1C1CCCC21)C1CNC(=O)N1C |r,TLB:15:14:12:9.10,8:9:12:14.18,THB:17:18:12:9.10| Show InChI InChI=1S/C21H28N2O3/c1-23-17(11-22-21(23)24)12-6-7-18(25-2)20(9-12)26-19-10-13-8-16(19)15-5-3-4-14(13)15/h6-7,9,13-17,19H,3-5,8,10-11H2,1-2H3,(H,22,24)/t13?,14?,15?,16?,17?,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]- rolipram binding to rat cerebral cortex membranes				J Med Chem 34: 291-8 (1991) BindingDB Entry DOI: 10.7270/Q2NV9MG8
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Rattus norvegicus)	BDBM50228825 (CHEMBL2112409) Show SMILES COc1ccc(cc1O[C@@H]1CC2CC1C1CCCC21)C1CNC(=O)N1C |r,TLB:15:14:12:9.10,8:9:12:14.18,THB:17:18:12:9.10| Show InChI InChI=1S/C21H28N2O3/c1-23-17(11-22-21(23)24)12-6-7-18(25-2)20(9-12)26-19-10-13-8-16(19)15-5-3-4-14(13)15/h6-7,9,13-17,19H,3-5,8,10-11H2,1-2H3,(H,22,24)/t13?,14?,15?,16?,17?,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of calcium-independent Phosphodiesterase 4				J Med Chem 34: 291-8 (1991) BindingDB Entry DOI: 10.7270/Q2NV9MG8
					More data for this Ligand-Target Pair