BDBM50228829 CHEMBL2111611

SMILES: COc1ccc(cc1O[C@H]1CC2CCC1C2)C1CNC(=O)N1C

InChI Key: InChIKey=GCEUBBGDHJJDSY-LUSXFMQSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Rattus norvegicus)	BDBM50228829 (CHEMBL2111611) Show SMILES COc1ccc(cc1O[C@H]1CC2CCC1C2)C1CNC(=O)N1C |r,THB:8:9:15:13.12| Show InChI InChI=1S/C18H24N2O3/c1-20-14(10-19-18(20)21)12-5-6-15(22-2)17(9-12)23-16-8-11-3-4-13(16)7-11/h5-6,9,11,13-14,16H,3-4,7-8,10H2,1-2H3,(H,19,21)/t11?,13?,14?,16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of cAMP-specific calcium-independent phosphodiesterase (IPDE).				J Med Chem 34: 291-8 (1991) BindingDB Entry DOI: 10.7270/Q2NV9MG8
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Rattus norvegicus)	BDBM50228829 (CHEMBL2111611) Show SMILES COc1ccc(cc1O[C@H]1CC2CCC1C2)C1CNC(=O)N1C |r,THB:8:9:15:13.12| Show InChI InChI=1S/C18H24N2O3/c1-20-14(10-19-18(20)21)12-5-6-15(22-2)17(9-12)23-16-8-11-3-4-13(16)7-11/h5-6,9,11,13-14,16H,3-4,7-8,10H2,1-2H3,(H,19,21)/t11?,13?,14?,16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]- rolipram binding to phosphodiesterase 4 of rat cerebral cortex membranes.				J Med Chem 34: 291-8 (1991) BindingDB Entry DOI: 10.7270/Q2NV9MG8
					More data for this Ligand-Target Pair