BDBM50228906 1-(4-(2-(1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2-oxoethyl)phenyl)piperidin-2-one::CHEMBL252651

SMILES: COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1)N1CCCCC1=O)C(F)(F)F

InChI Key: InChIKey=JCRVSHIYHZCJJR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50228906 (1-(4-(2-(1-(4-methoxyphenyl)-3-(trifluoromethyl)-1...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1)N1CCCCC1=O)C(F)(F)F Show InChI InChI=1S/C24H22F3N3O3/c1-33-19-11-9-18(10-12-19)30-20(15-22(28-30)24(25,26)27)21(31)14-16-5-7-17(8-6-16)29-13-3-2-4-23(29)32/h5-12,15H,2-4,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 18: 749-54 (2008) Article DOI: 10.1016/j.bmcl.2007.11.040 BindingDB Entry DOI: 10.7270/Q2DV1KQS
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50228906 (1-(4-(2-(1-(4-methoxyphenyl)-3-(trifluoromethyl)-1...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1)N1CCCCC1=O)C(F)(F)F Show InChI InChI=1S/C24H22F3N3O3/c1-33-19-11-9-18(10-12-19)30-20(15-22(28-30)24(25,26)27)21(31)14-16-5-7-17(8-6-16)29-13-3-2-4-23(29)32/h5-12,15H,2-4,13-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human thrombin				Bioorg Med Chem Lett 18: 749-54 (2008) Article DOI: 10.1016/j.bmcl.2007.11.040 BindingDB Entry DOI: 10.7270/Q2DV1KQS
					More data for this Ligand-Target Pair