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SMILES: CCC(C)(C)C(=O)NC(CO)c1ccccc1

InChI Key: InChIKey=OSEBUAWBKNVUKG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229028   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 1


(Homo sapiens (Human))		BDBM50229028
PNG
(CHEMBL4066793)
Show SMILES CCC(C)(C)C(=O)NC(CO)c1ccccc1
Show InChI InChI=1S/C14H21NO2/c1-4-14(2,3)13(17)15-12(10-16)11-8-6-5-7-9-11/h5-9,12,16H,4,10H2,1-3H3,(H,15,17)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 1.08E+3n/an/an/an/a



National Institute of Biological Sciences

Curated by ChEMBL


Assay Description
Inhibition of RIP1 in human HT-29 cells assessed as reduction in TNFalpha/z-VAD-FMK-induced necrosis after 24 hrs by Cell Titer-Glo luminescent cell ...

J Med Chem 60: 972-986 (2017)


BindingDB Entry DOI: 10.7270/Q2QC05QD
More data for this
Ligand-Target Pair