BDBM50229089 2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio)benzamide::CHEMBL253856

SMILES: Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(N)=O

InChI Key: InChIKey=DLMFUVADHVHUNY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229089 (2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio)...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(N)=O Show InChI InChI=1S/C16H14N4OS2/c1-10-5-6-11(8-12(10)15(17)21)22-14-9-19-16(23-14)20-13-4-2-3-7-18-13/h2-9H,1H3,(H2,17,21)(H,18,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair