BDBM50229099 CHEMBL253855::N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4-methylphenylthio)thiazol-2-yl)acetamide

SMILES: CC(=O)Nc1ncc(Sc2ccc(C)c(c2)C(=O)N2CCN(CC2)C(C)=O)s1

InChI Key: InChIKey=CUWZDYBXVJSLOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229099 (CHEMBL253855 | N-(5-(3-(1-acetylpiperazine-4-carbo...) Show SMILES CC(=O)Nc1ncc(Sc2ccc(C)c(c2)C(=O)N2CCN(CC2)C(C)=O)s1 Show InChI InChI=1S/C19H22N4O3S2/c1-12-4-5-15(27-17-11-20-19(28-17)21-13(2)24)10-16(12)18(26)23-8-6-22(7-9-23)14(3)25/h4-5,10-11H,6-9H2,1-3H3,(H,20,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair