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SMILES: Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCN(CC1)S(C)(=O)=O

InChI Key: InChIKey=SQHOMEGRFZMJBQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229104   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))		BDBM50229104
PNG
((2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio...)
Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCN(CC1)S(C)(=O)=O
Show InChI InChI=1S/C21H23N5O3S3/c1-15-6-7-16(30-19-14-23-21(31-19)24-18-5-3-4-8-22-18)13-17(15)20(27)25-9-11-26(12-10-25)32(2,28)29/h3-8,13-14H,9-12H2,1-2H3,(H,22,23,24)
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Similars
Article
PubMed
n/an/a 910n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of TrkA

Bioorg Med Chem Lett 18: 634-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.076
BindingDB Entry DOI: 10.7270/Q2JD4WJ5
More data for this
Ligand-Target Pair