BDBM50229107 CHEMBL253857::N-isopropyl-2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio)benzamide

SMILES: CC(C)NC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C

InChI Key: InChIKey=UIXCNKQZQFGSKI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229107 (CHEMBL253857 | N-isopropyl-2-methyl-5-(2-(pyridin-...) Show SMILES CC(C)NC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C19H20N4OS2/c1-12(2)22-18(24)15-10-14(8-7-13(15)3)25-17-11-21-19(26-17)23-16-6-4-5-9-20-16/h4-12H,1-3H3,(H,22,24)(H,20,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair