BindingDB logo
myBDB logout

null

SMILES: Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1NC(=O)CC#N

InChI Key: InChIKey=LILKIHSYEDHAMH-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229109   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))		BDBM50229109
PNG
(2-cyano-N-(2-methyl-5-(2-(pyridin-2-ylamino)thiazo...)
Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1NC(=O)CC#N
Show InChI InChI=1S/C18H15N5OS2/c1-12-5-6-13(10-14(12)22-16(24)7-8-19)25-17-11-21-18(26-17)23-15-4-2-3-9-20-15/h2-6,9-11H,7H2,1H3,(H,22,24)(H,20,21,23)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of TrkA

Bioorg Med Chem Lett 18: 634-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.076
BindingDB Entry DOI: 10.7270/Q2JD4WJ5
More data for this
Ligand-Target Pair