BDBM50229110 CHEMBL254062::N-(2-acetamidoethyl)-2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio)benzamide

SMILES: CC(=O)NCCNC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C

InChI Key: InChIKey=YLQWQDKNMRXXIZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229110 (CHEMBL254062 | N-(2-acetamidoethyl)-2-methyl-5-(2-...) Show SMILES CC(=O)NCCNC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C20H21N5O2S2/c1-13-6-7-15(11-16(13)19(27)23-10-9-21-14(2)26)28-18-12-24-20(29-18)25-17-5-3-4-8-22-17/h3-8,11-12H,9-10H2,1-2H3,(H,21,26)(H,23,27)(H,22,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair