BDBM50229208 CHEMBL427890::N-(4-(2,2,2-trifluoroethylsulfonamido)benzyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxamide

SMILES: Cc1nc(sc1C(=O)NCc1ccc(NS(=O)(=O)CC(F)(F)F)cc1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=XCEAPYBAZUFDTD-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50229208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50229208 (CHEMBL427890 | N-(4-(2,2,2-trifluoroethylsulfonami...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(NS(=O)(=O)CC(F)(F)F)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F6N3O3S2/c1-12-17(34-19(29-12)14-4-6-15(7-5-14)21(25,26)27)18(31)28-10-13-2-8-16(9-3-13)30-35(32,33)11-20(22,23)24/h2-9,30H,10-11H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta assessed as receptor activation by cell based assay				Bioorg Med Chem Lett 18: 710-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.053 BindingDB Entry DOI: 10.7270/Q2542NBN
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50229208 (CHEMBL427890 | N-(4-(2,2,2-trifluoroethylsulfonami...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(NS(=O)(=O)CC(F)(F)F)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F6N3O3S2/c1-12-17(34-19(29-12)14-4-6-15(7-5-14)21(25,26)27)18(31)28-10-13-2-8-16(9-3-13)30-35(32,33)11-20(22,23)24/h2-9,30H,10-11H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma assessed as receptor activation by cell based assay				Bioorg Med Chem Lett 18: 710-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.053 BindingDB Entry DOI: 10.7270/Q2542NBN
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50229208 (CHEMBL427890 | N-(4-(2,2,2-trifluoroethylsulfonami...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(NS(=O)(=O)CC(F)(F)F)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F6N3O3S2/c1-12-17(34-19(29-12)14-4-6-15(7-5-14)21(25,26)27)18(31)28-10-13-2-8-16(9-3-13)30-35(32,33)11-20(22,23)24/h2-9,30H,10-11H2,1H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at mouse PPARgamma assessed as receptor activation by cell based assay				Bioorg Med Chem Lett 18: 710-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.053 BindingDB Entry DOI: 10.7270/Q2542NBN
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50229208 (CHEMBL427890 | N-(4-(2,2,2-trifluoroethylsulfonami...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(NS(=O)(=O)CC(F)(F)F)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F6N3O3S2/c1-12-17(34-19(29-12)14-4-6-15(7-5-14)21(25,26)27)18(31)28-10-13-2-8-16(9-3-13)30-35(32,33)11-20(22,23)24/h2-9,30H,10-11H2,1H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at mouse PPARdelta assessed as receptor activation by cell based assay				Bioorg Med Chem Lett 18: 710-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.053 BindingDB Entry DOI: 10.7270/Q2542NBN
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50229208 (CHEMBL427890 | N-(4-(2,2,2-trifluoroethylsulfonami...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(NS(=O)(=O)CC(F)(F)F)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F6N3O3S2/c1-12-17(34-19(29-12)14-4-6-15(7-5-14)21(25,26)27)18(31)28-10-13-2-8-16(9-3-13)30-35(32,33)11-20(22,23)24/h2-9,30H,10-11H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha assessed as receptor activation by cell based assay				Bioorg Med Chem Lett 18: 710-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.053 BindingDB Entry DOI: 10.7270/Q2542NBN
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50229208 (CHEMBL427890 | N-(4-(2,2,2-trifluoroethylsulfonami...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(NS(=O)(=O)CC(F)(F)F)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F6N3O3S2/c1-12-17(34-19(29-12)14-4-6-15(7-5-14)21(25,26)27)18(31)28-10-13-2-8-16(9-3-13)30-35(32,33)11-20(22,23)24/h2-9,30H,10-11H2,1H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assay				Bioorg Med Chem Lett 18: 710-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.053 BindingDB Entry DOI: 10.7270/Q2542NBN
					More data for this Ligand-Target Pair