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SMILES: CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CSc1ccc(OC)cc1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=INSOHVGJKVCNCT-WCWDXBQESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229330   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1S


(Rattus norvegicus)		BDBM50229330
PNG
(CHEMBL308817)
Show SMILES CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CSc1ccc(OC)cc1)c1ccccc1C(F)(F)F |c:12,t:9|
Show InChI InChI=1S/C25H23F3N2O3S/c1-4-33-24(31)23-21(14-34-17-11-9-16(32-3)10-12-17)30-15(2)19(13-29)22(23)18-7-5-6-8-20(18)25(26,27)28/h5-12,22,31H,4,14H2,1-3H3/b24-23+
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 71n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine

J Med Chem 34: 2248-60 (1991)


BindingDB Entry DOI: 10.7270/Q27P91MK
More data for this
Ligand-Target Pair