BDBM50229707 CHEMBL4098578

SMILES: C(CN1CCOCC1)NCc1ccc(cc1)-c1ccc2C=CCNc2c1

InChI Key: InChIKey=CMKCZFMTWRNIJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50229707 (CHEMBL4098578) Show SMILES C(CN1CCOCC1)NCc1ccc(cc1)-c1ccc2C=CCNc2c1 |c:22| Show InChI InChI=1S/C22H27N3O/c1-2-20-7-8-21(16-22(20)24-9-1)19-5-3-18(4-6-19)17-23-10-11-25-12-14-26-15-13-25/h1-8,16,23-24H,9-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Rheinische Friedrich-Wilhelms-Universit£t Curated by ChEMBL					Assay Description Inhibition of tankyrase-2 (unknown origin)				J Med Chem 60: 1238-1246 (2017) BindingDB Entry DOI: 10.7270/Q2KK9F10
					More data for this Ligand-Target Pair