BDBM50229993 2-thiourea::CHEMBL260876::Thiocarbamid::Thioharnstoff::Thiokarbamid::carbonothioic diamide::thiocarbamide::thiocarbonic acid diamide::thiourea
SMILES: NC(N)=S
InChI Key: InChIKey=UMGDCJDMYOKAJW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 1.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
COMSATS Institute of Information Technology Curated by ChEMBL | Assay Description Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol method | Eur J Med Chem 46: 5473-9 (2011) Article DOI: 10.1016/j.ejmech.2011.09.009 BindingDB Entry DOI: 10.7270/Q2GM87QH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Karachi Curated by ChEMBL | Assay Description Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi... | Eur J Med Chem 74: 314-23 (2014) Article DOI: 10.1016/j.ejmech.2014.01.001 BindingDB Entry DOI: 10.7270/Q2VH5QBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | US Patent | 2.00E+4 | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
TBA US Patent | Assay Description Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ... | US Patent US9447057 (2016) BindingDB Entry DOI: 10.7270/Q2XG9Q2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 2.00E+4 | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Karachi | Assay Description Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ... | Bioorg Chem 64: 85-96 (2016) Article DOI: 10.1016/j.bioorg.2015.12.007 BindingDB Entry DOI: 10.7270/Q2GX49CF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Canavalia ensiformis (jack bean) urease assessed as release of ammonia after 30 min by indophenol method | Citation and Details Article DOI: 10.1007/s00044-012-0376-4 BindingDB Entry DOI: 10.7270/Q2P84FT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alcohol dehydrogenase (Equus caballus) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | 4.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition against horse liver alcohol dehydrogenase | J Med Chem 26: 916-22 (1983) BindingDB Entry DOI: 10.7270/Q2PR7Z5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea Amidohydrolase Subunit alpha (Bacillus pasteurii) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | 30 |
COMSATS Institute of Information Technology | Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 無 of buffers containing 100 mMol urea were incubated with 5 無... | Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | 6.8 | 30 |
University of Peshawar | Assay Description Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffer containing 100 mM urea were incubated with 5 &... | J Enzyme Inhib Med Chem 25: 296-9 (2010) Article DOI: 10.3109/14756360903179385 BindingDB Entry DOI: 10.7270/Q2TB15TQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-i-Azam University | Assay Description The synthesized compounds (4a-e, 5a-e) were tested for their in vitro urease inhibition activities at 0.2 mM concentration against jack bean urease. ... | J Enzyme Inhib Med Chem 25: 572-6 (2010) Article DOI: 10.3109/14756360903389864 BindingDB Entry DOI: 10.7270/Q25H7F5M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Khyber Medical College | Assay Description Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffers containing 100 mM urea were incubated with 5 ... | J Enzyme Inhib Med Chem 26: 480-4 (2011) Article DOI: 10.3109/14756366.2010.528415 BindingDB Entry DOI: 10.7270/Q2CZ3626 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | 6.8 | 30 |
Solapur University | Assay Description Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe... | J Enzyme Inhib Med Chem 28: 1316-23 (2013) Article DOI: 10.3109/14756366.2012.740477 BindingDB Entry DOI: 10.7270/Q2J965BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine-protein kinase ATM (Homo sapiens (Human)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of ATM | Proc Natl Acad Sci USA 104: 20523-8 (2007) Checked by Author Article DOI: 10.1073/pnas.0708800104 BindingDB Entry DOI: 10.7270/Q2DB82RH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mysore Curated by ChEMBL | Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production incubated at 30 degC for 15 mins by indophenol method | Eur J Med Chem 87: 657-61 (2014) Article DOI: 10.1016/j.ejmech.2014.09.098 BindingDB Entry DOI: 10.7270/Q21N82QR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA Puncak Alam Campus Curated by ChEMBL | Assay Description Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Weatherburn assay | Bioorg Med Chem Lett 25: 3285-9 (2015) BindingDB Entry DOI: 10.7270/Q2GT5PZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Islamia University of Bahawalpur Curated by ChEMBL | Assay Description Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol method | Bioorg Med Chem 23: 6049-58 (2015) BindingDB Entry DOI: 10.7270/Q2V40WZ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab Curated by ChEMBL | Assay Description Inhibition of jack beans urease assessed as hydrolysis of urea into ammonia preincubated for 10 mins followed by urea addition measured after 10 mins... | Eur J Med Chem 102: 464-70 (2015) BindingDB Entry DOI: 10.7270/Q2PV6N68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM) Curated by ChEMBL | Assay Description Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol method | Bioorg Med Chem 23: 7211-8 (2015) BindingDB Entry DOI: 10.7270/Q2W097RV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 2.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-i-Azam University Curated by ChEMBL | Assay Description Inhibition of jack bean urease using urea as substrate assessed as reduction in ammonia production after 30 mins by indophenol method | Bioorg Med Chem 24: 4452-4463 (2016) BindingDB Entry DOI: 10.7270/Q2VX0JF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
COMSATS Institute of Information Technology Curated by ChEMBL | Assay Description Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol method | Eur J Med Chem 46: 5473-9 (2011) Article DOI: 10.1016/j.ejmech.2011.09.009 BindingDB Entry DOI: 10.7270/Q2GM87QH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-i-Azam University Curated by ChEMBL | Assay Description Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol method | Eur J Med Chem 70: 487-96 (2013) Article DOI: 10.1016/j.ejmech.2013.10.012 BindingDB Entry DOI: 10.7270/Q2W097DC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Karachi Curated by ChEMBL | Assay Description Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol method | Eur J Med Chem 74: 314-23 (2014) Article DOI: 10.1016/j.ejmech.2014.01.001 BindingDB Entry DOI: 10.7270/Q2VH5QBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of ATR | Proc Natl Acad Sci USA 104: 20523-8 (2007) Checked by Author Article DOI: 10.1073/pnas.0708800104 BindingDB Entry DOI: 10.7270/Q2DB82RH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit beta (Helicobacter pylori) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kongju National University Curated by ChEMBL | Assay Description Inhibition of Campylobacter pylori urease preincubated for 5 mins followed by urea addition measured after 10 mins by Berthelot assay | Bioorg Med Chem 26: 3791-3804 (2018) Article DOI: 10.1016/j.bmc.2018.06.005 BindingDB Entry DOI: 10.7270/Q22R3V60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdogan University, Rize, Turkey. Electronic address: emre.mentese@erdogan.edu.tr. Curated by ChEMBL | Assay Description Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m... | Bioorg Med Chem Lett 27: 3014-3018 (2017) Article DOI: 10.1016/j.bmcl.2017.05.019 BindingDB Entry DOI: 10.7270/Q20004H0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Imam Abdulrahman Bin Faisal University Curated by ChEMBL | Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method | Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 6.83E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Karadeniz Technical University Curated by ChEMBL | Assay Description Inhibition of Jack bean urease using urea as substrate assessed as production of ammonia after 15 mins | Eur J Med Chem 67: 230-42 (2013) Article DOI: 10.1016/j.ejmech.2013.06.045 BindingDB Entry DOI: 10.7270/Q25T3PD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 6.83E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Karadeniz Technical University Curated by ChEMBL | Assay Description Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins | Eur J Med Chem 69: 622-31 (2013) Article DOI: 10.1016/j.ejmech.2013.07.040 BindingDB Entry DOI: 10.7270/Q20V8GRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Canavalia ensiformis (jack bean) urease assessed as inhibition of ammonia production after 15 min by indophenol method | Citation and Details Article DOI: 10.1007/s00044-013-0575-7 BindingDB Entry DOI: 10.7270/Q23N268X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Canavalia ensiformis (jack bean) urease using urea as substrate after 15 min by indophenol-based spectrophotometric analysis | Citation and Details Article DOI: 10.1007/s00044-011-9804-0 BindingDB Entry DOI: 10.7270/Q24B346S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a | 6.8 | 30 |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con... | Bioorg Chem 66: 80-7 (2016) Article DOI: 10.1016/j.bioorg.2016.03.010 BindingDB Entry DOI: 10.7270/Q20G3HXW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urea Amidohydrolase Subunit alpha (Bacillus pasteurii) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Hazara University | Assay Description This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ... | Bioorg Chem 63: 123-31 (2015) Article DOI: 10.1016/j.bioorg.2015.10.005 BindingDB Entry DOI: 10.7270/Q2H130RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.09E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Quaid-i-Azam University | Assay Description The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho... | Chem Biol Drug Des 87: 434-43 (2016) Article DOI: 10.1111/cbdd.12675 BindingDB Entry DOI: 10.7270/Q2CZ35X0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Quaid-I-Azam University | Assay Description Urease inhibition activity was determined by indophenol method. In brief, each 140 無 assay reaction contained 40 無 buffer (100 mM urea, 0.01 mM K2H... | Chem Biol Drug Des 85: 225-30 (2015) Article DOI: 10.1111/cbdd.12379 BindingDB Entry DOI: 10.7270/Q2P55M71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | n/a | n/a | 2.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-i-Azam University | Assay Description In vitro inhibition assay using jack bean urease. | J Enzyme Inhib Med Chem 24: 151-6 (2009) Article DOI: 10.1080/14756360801945598 BindingDB Entry DOI: 10.7270/Q29022CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease (Canavalia ensiformis (Jack bean) (Horse bean)) | BDBM50229993 (2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bahauddin Zakariya University | Assay Description Inhibition assay using urease from jack bean. | J Enzyme Inhib Med Chem 24: 437-46 (2009) Article DOI: 10.1080/14756360802188420 BindingDB Entry DOI: 10.7270/Q2HH6HPW | |||||||||||
More data for this Ligand-Target Pair |