BDBM50230418 CHEMBL260629::N(gamma)-hydroxy-L-arginine::N-OMEGA-HYDROXY-L-ARGININE::Nomega-hydroxy-L-arginine

SMILES: NC(NO)=NCCC[C@H]([NH3+])C([O-])=O

InChI Key: InChIKey=FQWRAVYMZULPNK-BYPYZUCNSA-N

Data: 1 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50230418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) Show SMILES NC(NO)=NCCC[C@H]([NH3+])C([O-])=O |r,w:4.4| Show InChI InChI=1S/C6H14N4O3/c7-4(5(11)12)2-1-3-9-6(8)10-13/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars		1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Arginase-1 (Bos taurus)	BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) Show SMILES NC(NO)=NCCC[C@H]([NH3+])C([O-])=O |r,w:4.4| Show InChI InChI=1S/C6H14N4O3/c7-4(5(11)12)2-1-3-9-6(8)10-13/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of bovine liver arginase				Bioorg Med Chem 16: 2305-12 (2008) Article DOI: 10.1016/j.bmc.2007.11.066 BindingDB Entry DOI: 10.7270/Q2KW5GXN
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Arginase-1 (Homo sapiens (Human))	BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) Show SMILES NC(NO)=NCCC[C@H]([NH3+])C([O-])=O |r,w:4.4| Show InChI InChI=1S/C6H14N4O3/c7-4(5(11)12)2-1-3-9-6(8)10-13/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) Show SMILES NC(NO)=NCCC[C@H]([NH3+])C([O-])=O |r,w:4.4| Show InChI InChI=1S/C6H14N4O3/c7-4(5(11)12)2-1-3-9-6(8)10-13/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	n/a	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a
University of Utrecht Curated by ChEMBL					Assay Description Binding affinity to iNOS with heme domain construct (unknown origin) assessed as spectral binding constant by spectral assay				Bioorg Med Chem Lett 19: 1758-62 (2009) Article DOI: 10.1016/j.bmcl.2009.01.076 BindingDB Entry DOI: 10.7270/Q2P55NC7
					More data for this Ligand-Target Pair
Arginase-1 (Rattus norvegicus)	BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) Show SMILES NC(NO)=NCCC[C@H]([NH3+])C([O-])=O |r,w:4.4| Show InChI InChI=1S/C6H14N4O3/c7-4(5(11)12)2-1-3-9-6(8)10-13/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair