Found 3 hits for monomerid = 50230505 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50230505
((S)-N-hydroxy-2-(pyridin-4-ylmethylamino)-3-(N-(4-...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](NCc2ccncc2)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C23H26N4O5S/c1-17-3-7-20(8-4-17)32-21-9-5-19(6-10-21)27(33(2,30)31)16-22(23(28)26-29)25-15-18-11-13-24-14-12-18/h3-14,22,25,29H,15-16H2,1-2H3,(H,26,28)/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
Bioorg Med Chem Lett 18: 1140-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50230505
((S)-N-hydroxy-2-(pyridin-4-ylmethylamino)-3-(N-(4-...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](NCc2ccncc2)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C23H26N4O5S/c1-17-3-7-20(8-4-17)32-21-9-5-19(6-10-21)27(33(2,30)31)16-22(23(28)26-29)25-15-18-11-13-24-14-12-18/h3-14,22,25,29H,15-16H2,1-2H3,(H,26,28)/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
Bioorg Med Chem Lett 18: 1140-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50230505
((S)-N-hydroxy-2-(pyridin-4-ylmethylamino)-3-(N-(4-...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](NCc2ccncc2)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C23H26N4O5S/c1-17-3-7-20(8-4-17)32-21-9-5-19(6-10-21)27(33(2,30)31)16-22(23(28)26-29)25-15-18-11-13-24-14-12-18/h3-14,22,25,29H,15-16H2,1-2H3,(H,26,28)/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of MMP1 |
Bioorg Med Chem Lett 18: 1140-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM |
More data for this Ligand-Target Pair | |