null

SMILES: CS(=O)(=O)N(C[C@H](N1CCS(=O)(=O)CC1)C(=O)NO)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1

InChI Key: InChIKey=UUKCYLIDEZGIBS-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50230515 ((S)-2-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-N-...) Show SMILES CS(=O)(=O)N(C[C@H](N1CCS(=O)(=O)CC1)C(=O)NO)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H24F3N3O7S2/c1-35(30,31)27(14-19(20(28)25-29)26-10-12-36(32,33)13-11-26)16-4-8-18(9-5-16)34-17-6-2-15(3-7-17)21(22,23)24/h2-9,19,29H,10-14H2,1H3,(H,25,28)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 18: 1140-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50230515 ((S)-2-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-N-...) Show SMILES CS(=O)(=O)N(C[C@H](N1CCS(=O)(=O)CC1)C(=O)NO)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H24F3N3O7S2/c1-35(30,31)27(14-19(20(28)25-29)26-10-12-36(32,33)13-11-26)16-4-8-18(9-5-16)34-17-6-2-15(3-7-17)21(22,23)24/h2-9,19,29H,10-14H2,1H3,(H,25,28)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem Lett 18: 1140-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM
					More data for this Ligand-Target Pair