Found 6 hits for monomerid = 50230517 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50230517
((S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)metha...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](O)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-12-3-7-14(8-4-12)25-15-9-5-13(6-10-15)19(26(2,23)24)11-16(20)17(21)18-22/h3-10,16,20,22H,11H2,1-2H3,(H,18,21)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of MMP9 |
Bioorg Med Chem Lett 18: 1140-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.129
BindingDB Entry DOI: 10.7270/Q2BP02JM |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50230517
((S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)metha...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](O)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-12-3-7-14(8-4-12)25-15-9-5-13(6-10-15)19(26(2,23)24)11-16(20)17(21)18-22/h3-10,16,20,22H,11H2,1-2H3,(H,18,21)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of MMP1 |
Bioorg Med Chem Lett 18: 1140-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.129
BindingDB Entry DOI: 10.7270/Q2BP02JM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50230517
((S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)metha...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](O)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-12-3-7-14(8-4-12)25-15-9-5-13(6-10-15)19(26(2,23)24)11-16(20)17(21)18-22/h3-10,16,20,22H,11H2,1-2H3,(H,18,21)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of catalytic domain MMP9 |
Bioorg Med Chem Lett 18: 1135-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.119
BindingDB Entry DOI: 10.7270/Q23X87HH |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50230517
((S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)metha...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](O)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-12-3-7-14(8-4-12)25-15-9-5-13(6-10-15)19(26(2,23)24)11-16(20)17(21)18-22/h3-10,16,20,22H,11H2,1-2H3,(H,18,21)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of full length MMP2 |
Bioorg Med Chem Lett 18: 1135-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.119
BindingDB Entry DOI: 10.7270/Q23X87HH |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50230517
((S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)metha...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](O)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-12-3-7-14(8-4-12)25-15-9-5-13(6-10-15)19(26(2,23)24)11-16(20)17(21)18-22/h3-10,16,20,22H,11H2,1-2H3,(H,18,21)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of catalytic domain MMP1 |
Bioorg Med Chem Lett 18: 1135-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.119
BindingDB Entry DOI: 10.7270/Q23X87HH |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50230517
((S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)metha...)Show SMILES Cc1ccc(Oc2ccc(cc2)N(C[C@H](O)C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-12-3-7-14(8-4-12)25-15-9-5-13(6-10-15)19(26(2,23)24)11-16(20)17(21)18-22/h3-10,16,20,22H,11H2,1-2H3,(H,18,21)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem Lett 18: 1140-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.129
BindingDB Entry DOI: 10.7270/Q2BP02JM |
More data for this
Ligand-Target Pair | |
Search and Browse
