null

SMILES: CS(=O)(=O)N(C[C@H](N1CCC(O)CC1)C(=O)NO)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1

InChI Key: InChIKey=BHIHZVBFDJREPF-FQEVSTJZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50230528 ((S)-N-hydroxy-2-(4-hydroxypiperidin-1-yl)-3-(N-(4-...) Show SMILES CS(=O)(=O)N(C[C@H](N1CCC(O)CC1)C(=O)NO)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C22H26F3N3O6S/c1-35(32,33)28(14-20(21(30)26-31)27-12-10-17(29)11-13-27)16-4-8-19(9-5-16)34-18-6-2-15(3-7-18)22(23,24)25/h2-9,17,20,29,31H,10-14H2,1H3,(H,26,30)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 18: 1140-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50230528 ((S)-N-hydroxy-2-(4-hydroxypiperidin-1-yl)-3-(N-(4-...) Show SMILES CS(=O)(=O)N(C[C@H](N1CCC(O)CC1)C(=O)NO)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C22H26F3N3O6S/c1-35(32,33)28(14-20(21(30)26-31)27-12-10-17(29)11-13-27)16-4-8-19(9-5-16)34-18-6-2-15(3-7-18)22(23,24)25/h2-9,17,20,29,31H,10-14H2,1H3,(H,26,30)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem Lett 18: 1140-5 (2008) Article DOI: 10.1016/j.bmcl.2007.11.129 BindingDB Entry DOI: 10.7270/Q2BP02JM
					More data for this Ligand-Target Pair