BDBM50230659 CHEMBL37549
SMILES: COc1ccc2[nH]cc(CCNC(=O)C3CC3)c2c1
InChI Key: InChIKey=HSOHROOUHRUSJR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Melatonin receptor (Homo sapiens (Human)) | BDBM50230659 (CHEMBL37549) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Urbino Curated by ChEMBL | Assay Description Inhibition of 2-[125I]iodomelatonin binding to melatonin receptor in quail brain as 1/Ka | J Med Chem 36: 4069-74 (1993) Article DOI: 10.1021/jm00077a010 BindingDB Entry DOI: 10.7270/Q2KP84VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50230659 (CHEMBL37549) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50230659 (CHEMBL37549) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0000500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Chimie Pharmaceutique Curated by ChEMBL | Assay Description Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane. | J Med Chem 37: 3231-9 (1994) Article DOI: 10.1021/jm00046a006 BindingDB Entry DOI: 10.7270/Q2S75K1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50230659 (CHEMBL37549) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Universite de Lille Curated by ChEMBL | Assay Description Binding affinity against Melatonin receptor using ovine pars tuberalis membranes of the pituitary. | J Med Chem 35: 1484-6 (1992) BindingDB Entry DOI: 10.7270/Q2B85BB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50230659 (CHEMBL37549) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.000453 | n/a | n/a | n/a | n/a | n/a |
Institut de Chimie Pharmaceutique Curated by ChEMBL | Assay Description Binding affinity to melatonin receptor measured on ovine pars tuberalis membrane | J Med Chem 37: 3231-9 (1994) Article DOI: 10.1021/jm00046a006 BindingDB Entry DOI: 10.7270/Q2S75K1J | |||||||||||
More data for this Ligand-Target Pair |