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SMILES: Clc1ccc(cc1)-c1nc(co1)C(=O)n1cccn1

InChI Key: InChIKey=LESKGVYPXMDPHA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231224   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50231224
PNG
(CHEMBL4091911)
Show SMILES Clc1ccc(cc1)-c1nc(co1)C(=O)n1cccn1
Show InChI InChI=1S/C13H8ClN3O2/c14-10-4-2-9(3-5-10)12-16-11(8-19-12)13(18)17-7-1-6-15-17/h1-8H
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



South China Agricultural University

Curated by ChEMBL


Assay Description
Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins

Bioorg Med Chem 25: 1852-1859 (2017)


BindingDB Entry DOI: 10.7270/Q2MG7RS3
More data for this
Ligand-Target Pair