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SMILES: COc1cccc(c1)-c1nc(co1)C(=O)n1cccn1

InChI Key: InChIKey=GVGPXPFFXHPKKI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231289   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50231289
PNG
(CHEMBL4096292)
Show SMILES COc1cccc(c1)-c1nc(co1)C(=O)n1cccn1
Show InChI InChI=1S/C14H11N3O3/c1-19-11-5-2-4-10(8-11)13-16-12(9-20-13)14(18)17-7-3-6-15-17/h2-9H,1H3
PDB

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PubMed
n/an/a 5.90E+3n/an/an/an/an/an/a



South China Agricultural University

Curated by ChEMBL


Assay Description
Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins

Bioorg Med Chem 25: 1852-1859 (2017)


BindingDB Entry DOI: 10.7270/Q2MG7RS3
More data for this
Ligand-Target Pair