BDBM50231290 CHEMBL4096961

SMILES: Brc1ccc(cc1)-c1nc(co1)C(=O)n1cccn1

InChI Key: InChIKey=QGZQDFNBAYQJSO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 and 5 (PDE4 and PDE5) (Homo sapiens (Human))	BDBM50231290 (CHEMBL4096961) Show SMILES Brc1ccc(cc1)-c1nc(co1)C(=O)n1cccn1 Show InChI InChI=1S/C13H8BrN3O2/c14-10-4-2-9(3-5-10)12-16-11(8-19-12)13(18)17-7-1-6-15-17/h1-8H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 25: 1852-1859 (2017) BindingDB Entry DOI: 10.7270/Q2MG7RS3
					More data for this Ligand-Target Pair