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BDBM50231309 CHEMBL4078947

SMILES: Fc1ccc(cc1)-c1nc(co1)C(=O)n1cccn1

InChI Key: InChIKey=FUFTUEHQOWHFTN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231309   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphodiesterase 4 and 5 (PDE4 and PDE5)


(Homo sapiens (Human))		BDBM50231309
PNG
(CHEMBL4078947)
Show SMILES Fc1ccc(cc1)-c1nc(co1)C(=O)n1cccn1
Show InChI InChI=1S/C13H8FN3O2/c14-10-4-2-9(3-5-10)12-16-11(8-19-12)13(18)17-7-1-6-15-17/h1-8H
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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Similars
PubMed
n/an/a 9.80E+3n/an/an/an/an/an/a



South China Agricultural University

Curated by ChEMBL


Assay Description
Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins

Bioorg Med Chem 25: 1852-1859 (2017)


BindingDB Entry DOI: 10.7270/Q2MG7RS3
More data for this
Ligand-Target Pair