BDBM50231317 CHEMBL4082110

SMILES: Cc1cc(C)n(n1)C(=O)c1coc(n1)-c1ccc(F)cc1

InChI Key: InChIKey=AIQSBYGDGNLYMU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 and 5 (PDE4 and PDE5) (Homo sapiens (Human))	BDBM50231317 (CHEMBL4082110) Show SMILES Cc1cc(C)n(n1)C(=O)c1coc(n1)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O2/c1-9-7-10(2)19(18-9)15(20)13-8-21-14(17-13)11-3-5-12(16)6-4-11/h3-8H,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 25: 1852-1859 (2017) BindingDB Entry DOI: 10.7270/Q2MG7RS3
					More data for this Ligand-Target Pair