BDBM50231320 CHEMBL4084152
SMILES: COc1ccc(cc1)-c1nc(co1)C(=O)n1cccn1
InChI Key: InChIKey=GEXFBNAQTYRBJC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50231320 (CHEMBL4084152) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University Curated by ChEMBL | Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]cAMP as substrate after 30 mins | Bioorg Med Chem 25: 1852-1859 (2017) BindingDB Entry DOI: 10.7270/Q2MG7RS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 4 and 5 (PDE4 and PDE5) (Homo sapiens (Human)) | BDBM50231320 (CHEMBL4084152) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University Curated by ChEMBL | Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins | Bioorg Med Chem 25: 1852-1859 (2017) BindingDB Entry DOI: 10.7270/Q2MG7RS3 | |||||||||||
More data for this Ligand-Target Pair |