BDBM50231361 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)urea::CHEMBL251822

SMILES: CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(C)[C@@H](C)[C@@H](O)c2ccccc2)cc(c1)-c1nnnn1C

InChI Key: InChIKey=IBXWXSQRMSFMKL-YHFSLCLQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50231361 (1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...) Show SMILES CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(C)[C@@H](C)[C@@H](O)c2ccccc2)cc(c1)-c1nnnn1C Show InChI InChI=1S/C25H35N7O3/c1-6-18-12-20(24-28-29-30-32(24)5)14-21(13-18)27-25(35)26-16(2)22(33)15-31(4)17(3)23(34)19-10-8-7-9-11-19/h7-14,16-17,22-23,33-34H,6,15H2,1-5H3,(H2,26,27,35)/t16-,17+,22+,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I] eotaxin from human CCR3 receptor in CHO cells				Bioorg Med Chem Lett 18: 586-95 (2008) Article DOI: 10.1016/j.bmcl.2007.11.087 BindingDB Entry DOI: 10.7270/Q2FF3S4K
					More data for this Ligand-Target Pair