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SMILES: CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](C)[C@@H](O)Cc1ccc(F)cc1

InChI Key: InChIKey=IKILZXIIPZFUMD-IFOZNXLVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231363   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50231363
PNG
(1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-h...)
Show SMILES CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](C)[C@@H](O)Cc1ccc(F)cc1
Show InChI InChI=1S/C25H34FN7O3/c1-5-33(17(3)22(34)13-18-9-11-20(26)12-10-18)15-23(35)16(2)27-25(36)28-21-8-6-7-19(14-21)24-29-30-31-32(24)4/h6-12,14,16-17,22-23,34-35H,5,13,15H2,1-4H3,(H2,27,28,36)/t16-,17+,22+,23+/m1/s1
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n/an/a 19n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Displacement of [125I] eotaxin from human CCR3 receptor in CHO cells

Bioorg Med Chem Lett 18: 586-95 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.087
BindingDB Entry DOI: 10.7270/Q2FF3S4K
More data for this
Ligand-Target Pair