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SMILES: CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C)[C@@H](C)[C@@H](O)Cc1ccc(F)cc1

InChI Key: InChIKey=JYQOPMMBCFIFTN-GXZJQHSTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231366   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50231366
PNG
(1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-h...)
Show SMILES CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C)[C@@H](C)[C@@H](O)Cc1ccc(F)cc1
Show InChI InChI=1S/C27H38FN7O3/c1-6-19-12-21(26-31-32-33-34(26)5)15-23(13-19)30-27(38)29-17(3)25(37)16-35(7-2)18(4)24(36)14-20-8-10-22(28)11-9-20/h8-13,15,17-18,24-25,36-37H,6-7,14,16H2,1-5H3,(H2,29,30,38)/t17-,18+,24+,25+/m1/s1
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Article
PubMed
n/an/a 1.20n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Displacement of [125I] eotaxin from human CCR3 receptor in CHO cells

Bioorg Med Chem Lett 18: 586-95 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.087
BindingDB Entry DOI: 10.7270/Q2FF3S4K
More data for this
Ligand-Target Pair