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SMILES: CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CNCCCc2ccc(F)cc2)cc(c1)-c1nnnn1C

InChI Key: InChIKey=UUGSRAAISBMNHE-ZHRRBRCNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231379   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50231379
PNG
(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Show SMILES CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CNCCCc2ccc(F)cc2)cc(c1)-c1nnnn1C
Show InChI InChI=1S/C24H32FN7O2/c1-4-17-12-19(23-29-30-31-32(23)3)14-21(13-17)28-24(34)27-16(2)22(33)15-26-11-5-6-18-7-9-20(25)10-8-18/h7-10,12-14,16,22,26,33H,4-6,11,15H2,1-3H3,(H2,27,28,34)/t16-,22+/m1/s1
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n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Displacement of [125I] eotaxin from human CCR3 receptor in CHO cells

Bioorg Med Chem Lett 18: 586-95 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.087
BindingDB Entry DOI: 10.7270/Q2FF3S4K
More data for this
Ligand-Target Pair