BDBM50231504 CHEMBL252025::N-{2-[2-(4-fluoro-phenyl)-5-(4-phenoxy-phenyl)-pyrrol-1-yl]-acetyl}-guanidine

SMILES: NC(=N)NC(=O)Cn1c(ccc1-c1ccc(Oc2ccccc2)cc1)-c1ccc(F)cc1

InChI Key: InChIKey=HMLZJVXASTZJHZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50231504 (CHEMBL252025 | N-{2-[2-(4-fluoro-phenyl)-5-(4-phen...) Show SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(Oc2ccccc2)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21FN4O2/c26-19-10-6-17(7-11-19)22-14-15-23(30(22)16-24(31)29-25(27)28)18-8-12-21(13-9-18)32-20-4-2-1-3-5-20/h1-15H,16H2,(H4,27,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of BACE1 by FRET assay				Bioorg Med Chem Lett 18: 1063-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.010 BindingDB Entry DOI: 10.7270/Q22807CT
					More data for this Ligand-Target Pair