BDBM50231772 5-(4-chlorophenyl)-N-[(1-methyl-1,2,3,4-tetrahydroquinolin)-6-yl]furan-2-carboxamide::CHEMBL250877

SMILES: CN1CCCc2cc(NC(=O)c3ccc(o3)-c3ccc(Cl)cc3)ccc12

InChI Key: InChIKey=JQDQZOXTHDIVIV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50231772 (5-(4-chlorophenyl)-N-[(1-methyl-1,2,3,4-tetrahydro...) Show SMILES CN1CCCc2cc(NC(=O)c3ccc(o3)-c3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C21H19ClN2O2/c1-24-12-2-3-15-13-17(8-9-18(15)24)23-21(25)20-11-10-19(26-20)14-4-6-16(22)7-5-14/h4-11,13H,2-3,12H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of hERG potassium channel expressed in CHO cells by isotope efflux assay				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50231772 (5-(4-chlorophenyl)-N-[(1-methyl-1,2,3,4-tetrahydro...) Show SMILES CN1CCCc2cc(NC(=O)c3ccc(o3)-c3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C21H19ClN2O2/c1-24-12-2-3-15-13-17(8-9-18(15)24)23-21(25)20-11-10-19(26-20)14-4-6-16(22)7-5-14/h4-11,13H,2-3,12H2,1H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair