null

SMILES: COC1=CC(=O)C(=O)C(CCCCCCCCO)=C1OC

InChI Key: InChIKey=ZHBZOZURNWAVFG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50231996 (CHEMBL4069339) Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCO)=C1OC |c:17,t:2| Show InChI InChI=1S/C16H24O5/c1-20-14-11-13(18)15(19)12(16(14)21-2)9-7-5-3-4-6-8-10-17/h11,17H,3-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Second University of Naples Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...				Eur J Med Chem 127: 715-726 (2017) BindingDB Entry DOI: 10.7270/Q2DR2XQ8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50231996 (CHEMBL4069339) Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCO)=C1OC |c:17,t:2| Show InChI InChI=1S/C16H24O5/c1-20-14-11-13(18)15(19)12(16(14)21-2)9-7-5-3-4-6-8-10-17/h11,17H,3-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Second University of Naples Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...				Eur J Med Chem 127: 715-726 (2017) BindingDB Entry DOI: 10.7270/Q2DR2XQ8
					More data for this Ligand-Target Pair