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SMILES: O=C(NC1CCc2cc(ccc12)N1CCCCC1)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=SVYGRCSOIPQXGO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232133   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50232133
PNG
(CHEMBL401128 | N-1H-indazol-4-yl-N'-(5-piperidin-1...)
Show SMILES O=C(NC1CCc2cc(ccc12)N1CCCCC1)Nc1cccc2[nH]ncc12 |w:3.2|
Show InChI InChI=1S/C22H25N5O/c28-22(24-19-5-4-6-21-18(19)14-23-26-21)25-20-10-7-15-13-16(8-9-17(15)20)27-11-2-1-3-12-27/h4-6,8-9,13-14,20H,1-3,7,10-12H2,(H,23,26)(H2,24,25,28)
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n/an/a 14n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux

J Med Chem 51: 392-5 (2008)


Article DOI: 10.1021/jm701007g
BindingDB Entry DOI: 10.7270/Q218367F
More data for this
Ligand-Target Pair