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SMILES: O=C(NC1CCc2c1cccc2N1CCOCC1)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=ASHXOMOCDINDTE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232145   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50232145
PNG
(1-(1H-Indazol-4-yl)-3-(4-morpholin-1-yl-indan-1-yl...)
Show SMILES O=C(NC1CCc2c1cccc2N1CCOCC1)Nc1cccc2[nH]ncc12 |w:3.2|
Show InChI InChI=1S/C21H23N5O2/c27-21(23-17-4-2-5-19-16(17)13-22-25-19)24-18-8-7-15-14(18)3-1-6-20(15)26-9-11-28-12-10-26/h1-6,13,18H,7-12H2,(H,22,25)(H2,23,24,27)
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n/an/a 65n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux

J Med Chem 51: 392-5 (2008)


Article DOI: 10.1021/jm701007g
BindingDB Entry DOI: 10.7270/Q218367F
More data for this
Ligand-Target Pair