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BDBM50232462 ADX-10059::RASEGLURANT::Raseglurant

SMILES: Cc1cc(C)c(N)c(n1)C#Cc1cccc(F)c1

InChI Key: InChIKey=MEDCLNYIYBERKO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232462   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50232462
PNG
(ADX-10059 | RASEGLURANT | Raseglurant)
Show SMILES Cc1cc(C)c(N)c(n1)C#Cc1cccc(F)c1
Show InChI InChI=1S/C15H13FN2/c1-10-8-11(2)18-14(15(10)17)7-6-12-4-3-5-13(16)9-12/h3-5,8-9H,17H2,1-2H3
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PC cid
PC sid
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Similars
PubMed
n/an/a 17n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL


Assay Description
Negative allosteric modulation of mGlu5 receptor (unknown origin)

Eur J Med Chem 127: 567-576 (2017)


BindingDB Entry DOI: 10.7270/Q2736T4T
More data for this
Ligand-Target Pair