BDBM50232725 1-ethyl-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2(1H)-one::CHEMBL254717

SMILES: CCn1c2ccccc2c(-c2ccncc2)c(-c2ccc(F)cc2)c1=O

InChI Key: InChIKey=UTJITVXBLPHLMA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50232725 (1-ethyl-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinoli...) Show SMILES CCn1c2ccccc2c(-c2ccncc2)c(-c2ccc(F)cc2)c1=O Show InChI InChI=1S/C22H17FN2O/c1-2-25-19-6-4-3-5-18(19)20(16-11-13-24-14-12-16)21(22(25)26)15-7-9-17(23)10-8-15/h3-14H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 18: 1431-5 (2008) Article DOI: 10.1016/j.bmcl.2007.12.073 BindingDB Entry DOI: 10.7270/Q208652M
					More data for this Ligand-Target Pair