BDBM50232936 CHEMBL4071738
SMILES: O=C(NC12CC3CC(CC(C3)C1)C2)c1cc(nn(C2CCCC2)c1=O)-c1ccccc1
InChI Key: InChIKey=RINTXKGYGCUYIV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50232936 (CHEMBL4071738) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 EBNA cell membranes after 90 mins by liquid scintillation and luminescence co... | Eur J Med Chem 127: 398-412 (2017) BindingDB Entry DOI: 10.7270/Q26W9D9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50232936 (CHEMBL4071738) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 EBNA cell membranes after 90 mins by liquid scintillation and luminescence co... | Eur J Med Chem 127: 398-412 (2017) BindingDB Entry DOI: 10.7270/Q26W9D9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50232936 (CHEMBL4071738) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari Curated by ChEMBL | Assay Description Inverse agonist activity at human CB2 receptor expressed in HEK293 EBNA cell membranes after 30 mins by [35S]-GTPgammaS binding assay | Eur J Med Chem 127: 398-412 (2017) BindingDB Entry DOI: 10.7270/Q26W9D9V | |||||||||||
More data for this Ligand-Target Pair |