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BDBM50233406 CHEMBL4082836

SMILES: CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)nc1

InChI Key: InChIKey=KHEPBWVZKOHFEI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233406   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hormone sensitive lipase


(Homo sapiens (Human))		BDBM50233406
PNG
(CHEMBL4082836)
Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)nc1
Show InChI InChI=1S/C25H24BF3N2O5/c1-23(2)24(3,4)36-26(35-23)19-7-5-6-8-20(19)31-22(32)16-9-14-21(30-15-16)33-17-10-12-18(13-11-17)34-25(27,28)29/h5-15H,1-4H3,(H,31,32)
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Similars
PubMed
n/an/a 24n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method

Bioorg Med Chem 25: 2234-2243 (2017)


BindingDB Entry DOI: 10.7270/Q2VH5R3W
More data for this
Ligand-Target Pair