BDBM50233680 4-(2'-hydroxymethyl-biphenyl-3-sulfonyl)-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL252794

SMILES: CSc1sc(cc1S(=O)(=O)c1cccc(c1)-c1ccccc1CO)C(N)=N

InChI Key: InChIKey=DLDUSKOAALOSDK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50233680 (4-(2'-hydroxymethyl-biphenyl-3-sulfonyl)-5-methyls...) Show SMILES CSc1sc(cc1S(=O)(=O)c1cccc(c1)-c1ccccc1CO)C(N)=N Show InChI InChI=1S/C19H18N2O3S3/c1-25-19-17(10-16(26-19)18(20)21)27(23,24)14-7-4-6-12(9-14)15-8-3-2-5-13(15)11-22/h2-10,22H,11H2,1H3,(H3,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Complement C1s subcomponent				Bioorg Med Chem Lett 18: 1603-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.064 BindingDB Entry DOI: 10.7270/Q2K35TD4
					More data for this Ligand-Target Pair