BDBM50233705 4-cyano-N-(2-(4-methylpiperidin-1-yl)-4-(piperazin-1-yl)phenyl)-1H-pyrrole-2-carboxamide::CHEMBL254908
SMILES: CC1CCN(CC1)c1cc(ccc1NC(=O)c1cc(c[nH]1)C#N)N1CCNCC1
InChI Key: InChIKey=YPPDZAOVZSJMKT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM50233705 (4-cyano-N-(2-(4-methylpiperidin-1-yl)-4-(piperazin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization | Bioorg Med Chem Lett 18: 1642-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.059 BindingDB Entry DOI: 10.7270/Q2FB52PS | |||||||||||
More data for this Ligand-Target Pair |