BDBM50233709 CHEMBL253027::N-(4-(1H-imidazol-1-yl)-2-(piperidin-1-yl)phenyl)-5-cyanofuran-2-carboxamide

SMILES: O=C(Nc1ccc(cc1N1CCCCC1)-n1ccnc1)c1ccc(o1)C#N

InChI Key: InChIKey=ZRIOTTIHUCWFGP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50233709 (CHEMBL253027 | N-(4-(1H-imidazol-1-yl)-2-(piperidi...) Show SMILES O=C(Nc1ccc(cc1N1CCCCC1)-n1ccnc1)c1ccc(o1)C#N Show InChI InChI=1S/C20H19N5O2/c21-13-16-5-7-19(27-16)20(26)23-17-6-4-15(25-11-8-22-14-25)12-18(17)24-9-2-1-3-10-24/h4-8,11-12,14H,1-3,9-10H2,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization				Bioorg Med Chem Lett 18: 1642-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.059 BindingDB Entry DOI: 10.7270/Q2FB52PS
					More data for this Ligand-Target Pair