BDBM50233823 CHEMBL4097807

SMILES: Oc1cccc(C(=O)Nc2cc([123I])cc(NC(=O)c3cccc(O)c3O)c2)c1O

InChI Key: InChIKey=BTOXGIYRUMZGEV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50233823 (CHEMBL4097807) Show SMILES Oc1cccc(C(=O)Nc2cc([123I])cc(NC(=O)c3cccc(O)c3O)c2)c1O Show InChI InChI=1S/C20H15IN2O6/c21-10-7-11(22-19(28)13-3-1-5-15(24)17(13)26)9-12(8-10)23-20(29)14-4-2-6-16(25)18(14)27/h1-9,24-27H,(H,22,28)(H,23,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of telomerase activity in human MDA-MB-435 cell lysate measured after 24 hrs by TRAP assay				Eur J Med Chem 125: 117-129 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X5V
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50233823 (CHEMBL4097807) Show SMILES Oc1cccc(C(=O)Nc2cc([123I])cc(NC(=O)c3cccc(O)c3O)c2)c1O Show InChI InChI=1S/C20H15IN2O6/c21-10-7-11(22-19(28)13-3-1-5-15(24)17(13)26)9-12(8-10)23-20(29)14-4-2-6-16(25)18(14)27/h1-9,24-27H,(H,22,28)(H,23,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of telomerase activity in human U2OS cell lysate measured after 24 hrs by TRAP assay				Eur J Med Chem 125: 117-129 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X5V
					More data for this Ligand-Target Pair